nanoXIM•Granules are spherical granules of synthetic hydroxyapatite available in two different particle ranges (0.5 - 1.0 and 1.0 - 2.0 mm). The high similarity of nano-hydroxyapatite to natural bone results in improved biological performance during bone regeneration.
nanoXIM•Granules with uniform size and spherical shape not only allows good flowability and handling properties, but also the formation of homogeneous intergranular pores.
|Able to fill irregular shaped hollows/cavities/defects|
|Good flowability and handling properties|
|Formation of homogeneous intergranular pores due to spherical shape|
|Highly homogeneous granules size|
|Hydroxyapatite with high phase purity|
|Available in two particle ranges|
nanoXIM•Granules are spherical granules composed of aggregates of synthetic nano-hydroxyapatite.
These granules are available in two particle ranges, 0.5 - 1.0 mm and 1.0 - 2.0 mm, so they can be used to create medical devices able to fill different and patient-specific bone defects.
|Reference||Particle range (mm)||Phase purity,
as Pb (ppm)
|nanoXIM•G1000||0.5 - 1.0||≥ 95||≤ 20|
|nanoXIM•G2000||1.0 - 2.0||≥ 95||≤ 20|
SEM image of nanoXIM•G1000
SEM image of nanoXIM•G2000
C.C. Coelho, T. Padrão, L. Costa, M.T. Pinto, P.C. Costa, V.F. Domingues, P.A. Quadros, F.J. Monteiro, S.R. Sousa, “The antibacterial and angiogenic effect of magnesium oxide in a hydroxyapatite bone substitute”, Scientific Reports, 10, 19098 (2020).
C.C. Coelho, R. Araújo, P.A. Quadros, S.R. Sousa, F.J. Monteiro, “Antibacterial bone substitute of hydroxyapatite and magnesium oxide to prevent dental and orthopaedic infections”, Materials Science and Engineering: C, 97, p. 529 (2019).