Recent research has demonstrated that smaller particles, such as nanoparticles and small microparticles, are far more effective than conventional micro-sized particles. Let’s dive deeper into how particle size impacts hydroxyapatite’s performance in dental applications, and why the size of HAp particles matters for treating sensitive teeth and preventing cavities!

‍

Dentin Tubule Occlusion

‍

Dentin tubules, the small channels within your teeth, play a key role in dental hypersensitivity. When these tubules are exposed due to enamel wear or damage, they can trigger pain, especially when consuming hot, cold, or acidic foods. The key to preventing this discomfort is effective tubule occlusion.

‍

In terms of size, conventional micro-sized hydroxyapatite particles, which can be over 5 microns (μm) in diameter, are simply too large to fill in the narrow 2.5 μm openings of dentin tubules. As a result, these larger particles fail to effectively seal the tubules and reduce sensitivity.

‍

The solution to this problem is nanoXIM!

‍

‍

The nanoXIM nano-HAp particles, which are significantly smaller (up to 50 times smaller than the average diameter of dentin tubules), are highly effective at occluding these channels. Similarly, nanoXIM micro-HAp particles, measuring around 1.1 μm, are still smaller than the average diameter of the tubules, enabling them to seal the openings effectively.

‍

‍

Hydroxyapatite Adhesion to Enamel

‍

In addition to occluding dentin tubules, hydroxyapatite’s ability to adhere to enamel is crucial for remineralization and the prevention of cavities. Research by Fabritius-Vilpoux et al. (2019) found that only particles with diameters up to 1.3 μm can successfully adhere to enamel. Traditional micro-HAp particles, which are typically larger than 5 μm, cannot do so, leading to poor remineralization and diminished protection against tooth decay.

‍

In contrast, nanoXIM nano-HAp particles, which are 25 times smaller than the 1.3 μm threshold, and nanoXIM micro-HAp particles, measuring at around 1.1 μm, are both within the ideal range for effective adhesion. These smaller particles bond strongly with enamel, promoting remineralization and enhancing the tooth's natural defenses.

‍

‍

In the world of dental health, particle size matters more than ever. The ability of hydroxyapatite to adhere to enamel and occlude dentin tubules is dramatically improved when the particles are small enough to fit into the narrow openings of these structures. nanoXIM nano-HAp and nanoXIM micro-HAp provide an effective solution to dental hypersensitivity and cavity prevention, offering superior performance over traditional micro-HAp particles.

‍

How do you know which nanoXIM product is best for you? It’s simple: nanoXIM CarePaste, which uses nanoXIM nano-HAp particles, is the recommended ingredient for aqueous formulations, best incorporated in toothpastes, gels, mouthwashes, and dental floss. On the other hand, nanoXIM CarePowder, which uses nanoXIM micro-HAp particles, is recommended for products that cannot include aqueous ingredients, such as tooth powders, tooth tablets, and chewing gums.

‍

By choosing products with smaller particle sizes, we can achieve better dental care results, leading to healthier teeth: remineralized and free from discomfort. Understanding the importance of particle size in hydroxyapatite formulations can lead to more effective treatments and better overall oral health.